Immune thrombocytopaenia as initial presentation of systemic lupus erythematosus: A case report and literature review
1 Department of Medicine, Faculty of Clinical Medicine, College of Health Sciences, Delta State University Abraka, Delta State, Nigeria.
2 Department of Internal Medicine, Delta State University Teaching Hospital, Oghara, Delta State, Nigeria.
3 Rheumatology Unit, Department of Internal Medicine, Delta State University Teaching Hospital, Oghara, Delta State, Nigeria.
4 Department of Pathology, Faculty of Clinical Medicine, College of Health Sciences, Delta State University Abraka, Delta State, Nigeria.
5 Heamatology unit, Department of Pathology, Delta State University Teaching Hospital, Delta State, Nigeria.
6 Department of Family Medicine, Faculty of Clinical Medicine, College of Health Sciences, Delta State University Abraka, Delta State, Nigeria.
7 Department of Family medicine, Delta State University Teaching Hospital, Oghara, Delta State, Nigeria.
Research Article
International Journal of Life Science Research Archive, 2024, 06(02), 045–051.
Article DOI: 10.53771/ijlsra.2024.6.2.0048
Publication history:
Received on 15 March 2024; revised on 04 May 2024; accepted on 07 May 2024
Abstract:
Immune Thrombocytopenic Purpura (ITP) may be the initial presentation of Systemic Lupus Erythematosus (SLE). We present a case report of a 22year old female who was a known patient with ITP diagnosed 6years previously at the Haematology unit when she had initially presented on account of petechial skin rashes and spontaneously bleeding gums worsened by brushing her teeth. She was then found to have a platelet count of zero with anemia and had been on intermittent steroid therapy till she developed recurrent joint pain necessitating referral to Rheumatology unit to evaluate for lupus. Further investigations revealed elevated autoantibodies suggestive of SLE. She was then commenced on Mycophenolate mofetil and Hydroxychloroquine.
Keywords:
Immune Thrombocytopenic Purpura; Systemic Lupus Erythematosus; Platelet Count; Mycophenolate Mofetil; Hydroxychloroquine
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