Study of Datura stramonium metallic nanoparticles showing anti-cancer and anti-microbial properties: A review
Alard College of Pharmacy, Marunje-411 057, PCMC, Pune, India.
Review
International Journal of Life Science Research Archive, 2025, 08(01), 001-009.
Article DOI: 10.53771/ijlsra.2025.8.1.0077
Publication history:
Received on 08 November 2024; revised on 18 December 2024; accepted on 21 December 2024
Abstract:
Datura stramonium metallic nanoparticles show anti-cancer and anti-microbial propensities: in vitro precedes in vivo rationale. Gold, silver, copper nanoparticles and zinc oxide nanoparticles were prepared using D. stramonium extracts by green synthesis methods owing to its vast phytochemical profile with major tropane alkaloids content.
The nanoparticles showed greater stability and biopotency as revealed by their higher cytotoxic potential against a number of cancer cell lines as well as antimicrobial activity against Gram-positive and Gram-negative bacteria.
This research shed more light on the potential of using D. stramonium-mediated nanoparticles as effective cancer therapeutic and antibacterial agents, paving ways for further therapeutic applications.
Keywords:
Datura stramonium; tropane alkaloids; metallic nanoparticles; anti-microbial properties; cancer therapy; anti-bacterial agents
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