Severe fusarium oxysporum keratomycosis: About 2 Cases
1 Department of parasitology, Hassan II University Hospital, Fez, Morocco.
2 Department of Ophtalmology , Hassan II University Hospital, Fez, Morocco
3 Faculty of Medicine and Pharmacy Sidi Mohammed Ben Abdellah, Fez, Morocco.
Research Article
International Journal of Life Science Research Archive, 2023, 05(02), 044–048.
Article DOI: 10.53771/ijlsra.2023.5.2.0096
Publication history:
Received on 30 September 2023; revised on 14 November 2023; accepted on 16 November 2023
Abstract:
Fungal keratitis is a destructive ocular infection, representing a serious diagnostic and therapeutic problem, difficult to treat and with poor results. It can cause irreversible damage.
Keratomycoses are rare and may be under-diagnosed. Direct microscopic examination and culture are essential for early specific diagnosis and must be taken into consideration to establish the most effective treatment and avoid serious complications. The pathogenesis of this infection is based on three factors: colonization, tissue damage and immunosuppression.
We report 2 cases of Fusarium oxysporum keratomycosis treated with amphotericin B. The diagnosis of corneal abscess was made after ophthalmological examination in 2 adult males with no previous ophthalmological history, referred to the Omar Drissi hospital in Fez for decreased visual acuity, photophobia, redness and intense pain in the right/left eye.
Corneal scrapings were taken for microbiological analysis, and after initial mycological results, local and systemic antifungal treatment was initiated with amphotericin B and natamycin eye drops. The evolution was marked by a corneal perforation with a tenon patch graft for the first patient, and healing for the 2nd
Keywords:
Keratitis; Fusarium; Oxysporum; Amphotericin B
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