Phytochemical screening and antimicrobial activity of Haematostaphis barteri
Department of Chemical Science, Federal University, Wukari Nigeria.
Research Article
International Journal of Science and Technology Research Archive, 2021, 01(02), 036–042.
Article DOI: 10.53771/ijstra.2021.1.2.0038
Publication history:
Received on 25August 2021; revised on 15 October 2021; accepted on 17 October 2021
Abstract:
The aim of this work was to carry out the phytochemical screening and antimicrobial activities of Haematostaphis barteri. The method of cold maceration was used in the extraction by serial exhaustive extraction method which involves successive extraction with solvents of increasing polarity from a non-polar (hexane) to a more polar solvent (methanol) to ensure that a wide polarity range of compound could be extracted. The results showed that flavonoids, terpenes, terpenes, tannins, and saponins are present in all the leaf extracts. The result of the antimicrobial activity obtained from the extracts of the leaf of Haematostaphis barteri revealed that all the crude extracts of the leaf inhibited or exhibited antibacterial activity against Salmonella paratyphi, Staphylococcus aureus, Escherichia coli, and Penicillium spp. All the extracts did demonstrate antimicrobial activity against Aspergillus niger. The plant H. barteri is commonly used traditionally for the treatment of diarrhoea, wound, headache, malaria, dysentery and fevers. The overall results confirm the significance of the use of the plant in traditional medicinal treatment of diarrhea, wound, headache, malaria, dysentery and fevers, in line with reported claims.
Keywords:
Antimicrobial; Haematostaphis barteri: Phytochemistry; Zing; Sensitivity and Inhibition
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