Role of melatonin in children with insomnia and ADHD: Mini-review
Assistant Professor, Chandigarh College of Pharmacy, Chandigarh Group of Colleges, Landran, Mohali-140307 (Punjab)-India.
Review
International Journal of Science and Technology Research Archive, 2021, 01(02), 010–012.
Article DOI: 10.53771/ijstra.2021.1.2.0039
Publication history:
Received on 28 July 2021; revised on 04 September 2021; accepted on 06 September 2021
Abstract:
Melatonin is a hormone released from the pineal gland. In numerous clinical studies it has been investigated exogenously to treat children suffering from insomnia with attention deficit hyperkinetic disorder (ADHD), taking methylphenidate. The main purpose was to alleviate sleep disturbances. Subjects were selected for clinical studies in ADHD children taking methylphenidate and suffering from insomnia. Melatonin was administered in children for few weeks before bedtime with defined sleep hygiene. Constant monitoring of sleep qualities was done either subjectively or objectively. The studies have reported its efficacy and safety. Moreover, melatonin has been reported to alleviate the symptoms of ADHD associated insomnia. It has shown its effects in terms of reduced sleep latency and better sleep quality. Moreover, no serious adverse effects were reported. Cognitive functions were not much affected. The clinical studies hypothesize that melatonin has the potential to normalize the sleep disorders in ADHD children.
Keywords:
Melatonin; ADHD; Insomnia; Children; Sleep latency
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