Our experience in cell therapy in surgical problems
Department of surgery, Veer Surendra Sai Institute of Medical Science and Research (VIMSAR), Odisha, India, 768017.
Research Article
International Journal of Science and Technology Research Archive, 2022, 03(01), 110–124.
Article DOI: 10.53771/ijstra.2022.3.1.0051
Publication history:
Received on 11 May 2022; revised on 23 June 2022; accepted on 25 June 2022
Abstract:
Aim: To study the effect and efficacy of autologous bone marrow cell therapy in various surgical pathologies of varied etiology which were refractory to conventional methods of management.
Material and method: Ethical committee clearance and informed consent of patients were taken. Two groups of each surgical pathologies were selected randomly. The patients in study group were treated by conventional methods followed by autologous bone marrow cell application locally, whereas patients in control group were treated by conventional methods only. The patients were then followed post-operatively and analyzed by statistical methods.
Result: Post-operatively the patients in study group experienced faster recovery by appearing good quality granulation tissue and rapid epithelisation and there was also significant reduction in local pain. Biopsy showed improved fibroblast, macrophages, neovascularisation and less necrosis per HPF in study group as comparison to control group.
Conclusion: Autologous bone marrow cell therapy is a novel method in the management of various surgical pathologies.
Keywords:
Autologous bone marrow cell therapy; Surgical problems; Carcinoma breast; Fistula in ano; Ulcer; Incisional hernia
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