Vinca (Catharanthus roseus) containing phytochemicals and pharmacological profile
1 Department of Pharmaceutical Chemistry, Matoshri College of Pharmacy Nashik, (MS), India.
2 Department of Pharmaceutics, KCT’s R. G. Sapkal College of pharmacy Nashik (MS), India.
Research Article
International Journal of Science and Technology Research Archive, 2023, 04(01), 274–283.
Article DOI: 10.53771/ijstra.2023.4.1.0027
Publication history:
Received on 03 January 2023; revised on 03 March 2023; accepted on 06 March 2023
Abstract:
Catharanthus roseus (Vinca plant) is an important plant having many medicinal uses. It is popularly known as Madagascar periwinkle. It is small in size perennial herbaceous evergreen plant that was native to the Madagascar island .It has attracted increasing attention due to it being shown to possess a range of phytochemicals with various biological activities such as antioxidant, antibacterial, antifungal, antidiabetic and anticancer properties. It delivers about 130 alkaloids predominantly ajmalcine, vinceine, resperine, vincristine, vinblastine and raubasin. Remarkably, vinblastine and vincristine isolated from this plant were the first plant-derived anticancer agents deployed for clinical use. This paper provides an overview of the traditional use and phytochemical profiles of C. roseus, and summarises updated techniques of the preparation of dried material, extraction and isolation of bioactive compounds from this plant. In addition, purported health benefits of the extracts and bioactive compounds derived from this plant were also addressed to support their potential as therapeutic agents.
Keywords:
Catharanthus roseus; Bioactive compounds; Phytochemicals; Alkaloids; Health benefits
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